Function-guided renal parenchyma preservation in a giant bilateral Wilms tumor following SIOP-2016–based multistage chemotherapy and staged surgery: a case-based review

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Published: 2026-06-30
DOI: https://doi.org/10.64288/3mea5y68
Keywords:
bilateral Wilms tumor; nephron-sparing surgery; renal scintigraphy; kidney preservation; SIOP

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Ramin Malikov
Department of Pediatric Surgery, National Center of Oncology, Baku, Azerbaijan
https://orcid.org/0009-0009-2858-9383
Kamal Quliyev
Intensive Care Unit, Baku Medical Plaza, Baku, Azerbaijan
https://orcid.org/0009-0001-9029-6882
Gambar Ismayilov
Department of Pediatric Surgery, National Center of Oncology, Baku, Azerbaijan
https://orcid.org/0009-0000-4283-3893
Iqbal Babazde
Military Medical Faculty, Azerbaijan Medical University, Baku, Azerbaijan
https://orcid.org/0009-0004-8400-1867

Abstract

Synchronous bilateral Wilms tumor (BWT) demands oncologic control while protecting lifelong kidney function. In mesenchymal-predominant tumors, radiologic shrinkage after neoadjuvant therapy may be minimal and can mislead size-based surgical sequencing. In BWT with discordant radiologic response, split renal function can decisively guide sequencing and expand nephron preservation.

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Vol. 2 No. 2 (2026): Vol.2 No.2

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Articles
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This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

Function-guided renal parenchyma preservation in a giant bilateral Wilms tumor following SIOP-2016–based multistage chemotherapy and staged surgery: a case-based review. (2026). MedEpicent: Journal of Medical Education and Clinical Research, 2(2). https://doi.org/10.64288/3mea5y68