Function-guided renal parenchyma preservation in a giant bilateral Wilms tumor following SIOP-2016–based multistage chemotherapy and staged surgery: a case-based review
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Synchronous bilateral Wilms tumor (BWT) demands oncologic control while protecting lifelong kidney function. In mesenchymal-predominant tumors, radiologic shrinkage after neoadjuvant therapy may be minimal and can mislead size-based surgical sequencing. In BWT with discordant radiologic response, split renal function can decisively guide sequencing and expand nephron preservation.
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Function-guided renal parenchyma preservation in a giant bilateral Wilms tumor following SIOP-2016–based multistage chemotherapy and staged surgery: a case-based review. (2026). MedEpicent: Journal of Medical Education and Clinical Research, 2(2). https://doi.org/10.64288/3mea5y68